Main Information
- Drug : Boldenone Undecylenate
- What is : An anabolic steroid derived from testosterone
- Concentrarion : 200mg / ml
- Package : 10ml Vial
- Excipients : Benzyl Benzoate, Benzyl Alcohol, Cottonseed oil
- Aspect : Clear, yellowish liquid
- Pharmaceutical form : Sterile oleaginous solution
- Administrarion : Deep intramuscular injection
Synonyms
- Equipoise
- Ganabol
- Parenabol
- Vebonol
- Boldefarm
Descripition
A sterile oleaginous solution containing per mL: Boldenone Undecylenate 200 mg with Benzyl Alcohol as preservative, Benzyl Benzoate solubilizer, in Cottonseed Oil q.s.
Boldenone Undecylenate , when injected, provides a peak release of the base steroid, within a few days after injection and sustain hormone release for approximately 3-4 weeks.
Boldenone acts similarly to testosterone, although it is much less estrogenic. It does also carry a more favorable balance towards anabolism than androgenism.
Boldenone also differs from testosterone in its lower ability to interact with the 5-alpha reductase enzyme. This is the enzyme responsible for forming di-hydrotestosterone from testosterone, which is a much more potent activator of the androgen receptor, causing acne, retention of fluids, baldness and prostate enlargement. Being in this aspect safer than testosterone.
Once metabolized, the drug increases nitrogen uptake by muscles, consequently increasing the protein synthesis. Besides that, Boldenone Undecyleate also stimulates appetite, reduces the fat amount deposits, and decreases catabolism.
Indications
The activity of boldenone is mainly anabolic, with a low androgenic potency. The drug is commonly used in doping within bodybuilding. If intended to assist in bodybuilding, the drug is taken as part of a steroid stack of other anabolic steroids, usually with a potent androgen like testosterone as the 'base' of the stack.
Boldenone Undecylenate is indicated for:
- To promote protein anabolism
- Osteoporosis
- Refractory deficient red cell production anemias
- Breast carcinoma
- Hereditary angioedema
- Antithrombin III deficiency
- Fibrinogen excess
- Growth failure
- Turner's syndrome
Contraindications
- Male patients with carcinoma of the breast or with known or suspected carcinoma of the prostate.
- Carcinoma of the breast in females with hypercalcemia: androgenic anabolic steroids may stimulate osteolytic resorption of bones.
- Pregnancy, because of masculinization of the fetus.
- Nephrosis or the nephrotic phase of nephritis.
Women should be observed for signs of virilization (deepening of the voice, hirsutism, acne,clitorimegaly and menstrual irregularities). Discontinuation of drug therapy at the time of evidence of mild virilism is necessary to prevent irreversible virilization. Such virilization is usual following anabolic steroid use in high doses. The insulin or oral hypoglycemic dosage may need adjustment in diabetic patients who receive anabolic steroids
Drug Interactions
When administered concurrently, the following drugs may interact with androgens :
- Anticoagulants, oral : C-17 substituted derivatives of testosterone, have been reported to decrease the anticoagulant requirement. Patients receiving oral anticoagulant therapy require close monitoring especially when androgens are started or stopped.
- Antidiabetic drugs and insulin : In diabetic patients, the metabolic effects of androgens may decrease blood glucose and insulin requirements.
- ACTH and corticosteroids : Enhanced tendency toward edema. Use caution when giving these drugs together, especially in patients with hepatic or cardiac disease.
- Oxyphenbutazone : Elevated serum levels of oxyphenbutazone may result.
Dosage
Boldenone Undecylenate is intended for deep intramuscular injection only, into the gluteal muscle preferably. Dosage should be based on therapeutic response and consideration of the benefit to risk ratio. Duration of therapy will depend on the response of the condition and the appearance of adverse reactions.
- Males : A dose of 200 to 400 mg once a week.
- Females : A dose of 50 to 100 mg once a week.
Adverse Reactions
- Postpubertal : Inhibition of testicular function, testicular atrophy and oligospermia, impotence, chronic priapism, epididymitis and bladder irritability.
- In women : Clitoral enlargement, menstrual irregularities. In both sexes : Increased or decreased libido.
- CNS : Habituation, excitation, insomnia, depression.
- Gastrointestinal : Nausea, vomiting, diarrhea.
- Hematologic : Bleeding in patients on concomitant anticoagulant therapy.
- Breast : Gynecomastia.
- Larynx : Deepening of the voice in women.
- Hair : Hirsutism and male pattern of baldness in women.
- Skin : Acne (especially in women and prepubertal boys.
- Skeletal : Premature closure of epiphyses in children.
- Fluid and Electrolytes : Edema, retention of serum electrolytes (sodium, chloride, potassium, phosphate, calcium).
- Metabolic/Endocrine : Decreased glucose tolerance , increased serum levels of low-density lipoprotein and decreased levels of high-density lipoprotein, increased creatine and creatinine excretion, increased serum levels of creatinine phosphokinase (CPK).
Some virilizing changes in women are irreversible even after prompt discontinuance of therapy and are not prevented by concomitant use of estrogens
Storage
Boldenol 200 should be stored at 20° to 25°C (68° to 77°F).
Warming and rotating the vial between the palms of the hands will redissolve any crystals that may have formed during storage at low temperatures.
History
Boldenone Undecylenate is a testosterone derived anabolic androgenic steroid that is best known by the trade name Equipoise given to it by Squibb in the 1970's. While Equipoise is officially classified as a veterinarian grade anabolic steroid, the first batches of Boldenone were introduced on the human grade pharmaceutical market by Ciba in the early 1950's under the brand name Parenabol. Human grade Boldenone would see some success in human medicine through the 1960's and 70's but would ultimately be discontinued by the end of the decade. Since that time, the steroid has only been available through veterinarian medicine and underground labs with the Equipoise name dominating the market. Fort Dodge Animal Health now owns the Equipoise name.
For decades, it has been assumed that Boldenone Undecylenate was very similar to Nandrolone Decanoate. This assumption was in part based on comments the late Dan Duchaine made about the steroid. However, the two compounds are not similar in any way; in fact, Duchaine would recant the statement, but the initial statement has been enough to keep the rumor alive. If Boldenol shares anything in common with another anabolic steroidal hormone, it would be testosterone, but Boldenone Undecylenate as it's commonly known is unique in its own right. An important note regarding the differences in these two steroidal hormones; Nandrolone carries a strong progestin nature, while Boldenone carries no progestin characteristics.
Functions
Boldenone Undecylenate is a structurally altered form of testosterone. It is a very slight change in an added double bond at the carbon one and two position. This double bond greatly reduces the hormone's androgenicity, as well as estrogenic nature. It is then attached to the very large or long Undecylenate ester, which is responsible for controlling the release of the hormone once administered into the body. The Undecylenate ester allows for a peak release in Boldenone approximately 3-4 days after injection, with a slow continuous release of the hormone to follow for approximately 21 days.
Due to its structural change, Boldenone Undecylenate only aromatizes at approximately 50% the rate of testosterone. Estrogenic side effects are possible, but the odds are highly in the individual's favor compared to testosterone. It is not as powerful of a mass builder as testosterone, not even close, but the reduced estrogenic activity should allow the individual to make cleaner gains through supplementation.
Boldenone Undecylenate shares many similarities regarding direct enhancement properties with testosterone. Common shared properties include its ability to enhance protein synthesis, nitrogen retention in the muscles, inhibit glucocorticoid hormones and increase IGF-1 output. Boldenone Undecylenate is also well known for increasing red blood cell count, a trait shared by most all anabolic steroids. However, issues of concern have been noted regarding how much Boldenone Undecylenate can increase red blood cell count. But available data tends to support this only being a concern with extremely high dose use for extremely long periods of time. In many ways, the increase in red blood cells provided by Boldenone Undecylenate can be fast and rapid, but may not present a significant advantage or disadvantage compared to most anabolic steroids when used responsibly. Without question, a moderate increase in cell production would be very advantageous for most any athlete.
Effects
The effects of Boldenone Undecylenate are fairly straightforward. This is a generally well-tolerated anabolic steroid that presents notable anabolic activity in most users in a clean and even fashion. Outside of performance enhancement use, Boldenone did enjoy some success as a human grade steroid for a time. The steroid had some success in treating muscle wasting diseases and osteoporosis, but would ultimately give way to other steroidal options. As a veterinarian steroid, Boldenone Undecylenate is well-known for its use in horses, hence the name "Equipoise" and its similarity to the word "Equestrian." EQ is often given to horses in an effort to increase lean body weight, which is in part due to the steroid's ability to increase appetite. An increased appetite is well noted among many performance enhancing athletes that use Boldenone Undecylenate, however, it doesn't appear to affect everyone the same. Many who use the anabolic steroid report no increase in appetite, it tends to be highly individualistic, but it could be useful for those struggling to consume needed calories.
As an off-season bulking steroid, Boldenone Undecylenate can add quality lean mass gains, but they will not come overnight, and will fall short of many anabolic steroids. Steroids like Nandrolone Decanoate will produce far greater mass results, as will steroids like Anadrol and Dianabol; however, the latter two are often accompanied by large amounts of water retention. Some athletes have, however, reported stronger off-season gains when Boldenone Undecylenate is added to a total off-season stack rather than used as a base steroid. If appetite suppression is an issue, this steroid may very well help you consume the excess calories needed for off-season growth. Of course, while it may not be a tremendous mass building steroid, for some it may produce all the mass they want. Not everyone who uses anabolic steroids is looking for immense gains in size.
Boldenone Undecylenate is also well-noted for promoting increases in strength. An increase in strength can be very beneficial to an off-season mass plan, but perhaps more beneficial to the enhancement of athletic performance. Unfortunately, the extremely long detection time will prohibit many athletes from using this product. Total detection time can stretch to five months. However, the steroid definitely provides numerous advantages to the athlete, not only in an increase in strength but a notable increase in muscular endurance. Recovery should also be enhanced. Regardless of the desired purpose of use, all who supplement with Boldenone Undecylenate will enjoy these related benefits.
Boldenone Undecylenate can also be used as a cutting steroid; in fact, this may be the most beneficial point of use. This anabolic steroid is an excellent protectant of lean muscle mass. In order to lose body fat, you must burn more calories than you consume, you must be in a caloric deficit, and this will hold true with or without anabolic steroid use. Unfortunately, a calorie deficit puts our lean muscle tissue at risk as the body will often take what it needs in order to meet its energy demands from our lean tissue. Proper dieting can greatly protect our lean muscle mass, but it can only go so far. Without the introduction of an anabolic steroid, some muscle mass will eventually and inevitably be lost. Boldenone Undecylenate will greatly protect you from this loss in lean tissue, and it has also been shown to have some very nice conditioning effects on the physique. Such effects will be greatly enhanced when combined with a non-aromatizing steroid like Masteron (Drostanolone) or Trenbolone. However, during most cutting plans of a competitive bodybuilding nature, while Boldenone Undecylenate is commonly used it is normally only used at the frontend of the cutting cycle. It will normally be discontinued during the later half of the plan due to possible estrogenic activity. While total estrogenic activity should be low, during this phase of supplementation any and all estrogenic activity is normally avoided or at least minimized to the lowest point possible.
Side Effects
Boldenone Undecylenate is a generally well-tolerated anabolic steroid for most men, and is often very well-tolerated by many women when low doses are applied. Side effects of Boldenone Undecylenate use are certainly possible, but most healthy adults should find this anabolic steroid very manageable. In order to help you understand the possible side effects of Boldenone Undecylenate use as well as their management, we have broken them down into their specific categories along with all the related information you'll need.
- Estrogenic : The Boldenone hormone does not aromatize heavily, but it is aromatized to estrogen nonetheless. This is due to the testosterone hormone's interaction with the aromatase enzyme. High levels of estrogen can prove problematic in their promotion of gynecomastia, excess water retention and high blood pressure if water retention becomes severe. Due to the moderate level of aromatizing activity, most men should find related side effects very easy to control. Moderate doses should be manageable, but many will find high doses to require added attention.
In order to combat the estrogenic side effects of Boldenone Undecylenate, an anti-estrogen medication is sometimes needed. Not all will need an anti-estrogen when using this steroid, but it's always a good idea to at least have one on hand. The anti-estrogen medications you can choose include Selective Estrogen Receptor Modulators (SERM's) like Nolvadex (Tamoxifen Citrate) and Aromatase Inhibitors (AI's) like Arimidex (Anastrozole). AI's will prove to be the most effective as they inhibit the aromatase process and lower total serum estrogen levels. Unfortunately, they can have a negative impact on cholesterol, which is further enhanced by the use of an aromatizing steroid. SERM's are not as effective, but they are often enough for many men. SERM's will not inhibit the aromatase process from occurring, but rather bind at the estrogen receptor preventing the hormone itself from binding. As an added bonus, SERM's may actually improve cholesterol levels due to their promotion of estrogenic activity in the liver. SERM's should be your first choice due to potential cholesterol issues AI's if they can get the job done.
- Androgenic : Boldenone Undecylenate can produce androgenic side effects such as acne, accelerated hair loss in those predisposed to male pattern baldness and body hair growth. However, the overall androgenicity of this steroid is greatly reduced due to the structural nature that creates Boldenone Undecylenate in its double bond at the carbon one and two position. Such side effects of Boldenone Undecylenate are still possible, but they will be strongly linked to genetic predisposition, but most will find the threshold is fairly high.
When combating the possible androgenic side effects of Boldenone Undecylenate, it's important to note they are brought on by the steroid being metabolized by the 5-alpha reductase enzyme. This metabolism will reduce Boldenone to an extremely potent androgen in dihydroboldenone, far more potent than dihydrotestosterone (DHT); however, the total dihydroboldenone activity has proven to be extremely low in human beings. You will further find the androgenic nature of Boldenone will not be significantly affected by 5-alpha reductase inhibitors like Finasteride that are often used to combat the reduction to DHT.
Due to the androgenic nature of Boldenone Undecylenate, women may potentially experience virilization symptoms. Virilization symptoms may include body hair growth, a deepening of the vocal chords and clitoral enlargement. However, the low androgenicity will make this steroid possible to use for some women without such symptoms. At the same time, the extremely slow acting nature of the compound can make it difficult to control regarding blood levels, and alternative steroids may be preferred. Without question, individual sensitivity will dictate a lot. If Boldenone Undecylenate is used and virilization symptoms begin to show, use should be discontinued immediately at their onset and they will fade away. If symptoms begin to show and are ignored, the symptoms may become irreversible.
- CardiovascularThe relative cardiovascular strain brought on by Boldenone Undecylenate should be much less than many anabolic steroids, especially those of an oral nature. Boldenone does have the ability to negatively affect cholesterol ratios, particularly in its ability to suppress HDL levels. However, it should not be of an extreme nature, and should be well within the realm of control for most healthy adults. Of course, the introduction of an AI to combat estrogenic effects will potentially enhance the improper lipid profiles, and should be considered when planning your cholesterol management.
All those who supplement with Boldenone Undecylenate as with all anabolic steroids should keep a close eye on their cholesterol levels, and should ensure they are healthy enough for use before supplementation begins. A cholesterol friendly lifestyle will be very important and should protect most who use Boldenone Undecylenate. Ensure your diet is cholesterol friendly and includes plenty of omega fatty acids. Incorporating plenty of cardiovascular activity is also highly advised.
- Testosterone : Like all anabolic steroids, Boldenone Undecylenate will suppress natural testosterone production. The rate of suppression varies from one steroid to the next, and while Boldenone Undecylenate is not the most suppressive steroid it will produce a significant reduction in total serum testosterone levels. For this reason, most men will need to include exogenous testosterone in their total stack when using Boldenone Undecylenate. The form of testosterone is inconsequential. All that matters is your body receives the testosterone it needs in order to prevent a low testosterone condition. A low testosterone condition can be very problematic, it carries numerous possible symptoms and is extremely unhealthy. If testosterone is used as a base steroid in your cycle, suppression will not be a concern. However, if testosterone does not represent a base, you should ensure you apply a minimum testosterone replacement therapy related dose based on the testosterone compound you choose.
Once the use of Boldenone Undecylenate has come to an end and all the exogenous steroidal hormones have cleared your system, natural testosterone production will begin again. The revived production will occur on its own, but a Post Cycle Therapy (PCT) plan is often recommended. A PCT plan will stimulate natural testosterone production and promote a more efficient recovery. It will not bring your testosterone levels back to where they were prior to anabolic steroid use, but it will provide an advantage. A well-planned PCT will ensure you have enough testosterone for proper bodily function while your levels continue to naturally rise. It should also significantly cut down the total time to full testosterone recovery; however, total recovery still may take several months post PCT.
Important notes on natural testosterone recovery and Boldenone Undecylenate use, as well as anabolic steroids in general. Natural recovery assumes no prior low testosterone level existed. It also assumes severe damage was not done to the Hypothalamic-Pituitary-Testicular-Axis (HPTA) due to improper anabolic steroid supplementation practices. For those who include Boldenone Undecylenate in their cycle, your PCT plan should begin approximately 2 weeks after your last steroid injection, assuming the cycle ended with Boldenone Undecylenate. Many will find beginning HCG use ten days after the final injection to be the best route to follow, while following HCG use with SERM therapy. Alternatively, some may choose to end their Boldenone Undecylenate use well before the total conclusion of a cycle, end the cycle with only small ester base steroids and enable them to begin their PCT plan much sooner.
- Hepatotoxicity : Boldenone is not a hepatotoxic anabolic steroid and will present no stress or damage to the liver.
Administration
Standard Boldenone Undecylenate doses will normally fall in the 200-400mg per week range. Most men will find 400mg to be very well-tolerated and generally the minimal amount of Boldenone Undecylenate they'll want to use. Many will also find 600mg per week to be extremely well-tolerated with side effects being extremely easy to control. However, such doses will increase estrogenic potential. Due to the long activity of the steroid, most men could easily get by with one injection per week, but splitting the weekly dose into 2-3 smaller injections will cut down on total injection volume. Further, some have reported side effects are even easier to control with a smaller more frequent injection schedule despite an extremely long half-life.
Regardless of the total dose, Boldenone Undecylenate should be used for a minimum of 8 weeks. This is a very common duration of use in cutting cycles. Many cutting plans will begin with 8 weeks of Boldenone Undecylenate with an additional 4-8 weeks without the hormone opting for non-aromatizing agents. During the off-season period of use, 8 weeks will again be the minimum, but most will find 12 weeks to be far more efficient. Bulking or cutting, you will find Boldenone Undecylenate to be an extremely versatile anabolic steroid that stacks well with all anabolic steroids.
For female use, 50mg of Boldenone Undecylenate per week is a standard dose. Virilization is avoidable with this dose but will be highly dependent on sensitivity. Some women may be able to tolerate 75-100mg per week, but should not attempt such a dose until they have become comfortable with 50mg per week. Most women will also find 6 week cycles of Boldenone Undecylenate to be as far as they want to take it, with occasional 8 week runs by those who tolerate the hormone well.
Reviews
Boldenone Undecylenate is a very versatile anabolic steroid that can be used for numerous purposes. We would not call it the most valuable or powerful anabolic steroid of all time, but in some circles it has received an undue poor reputation. This is in part due to the massive amount of counterfeit Boldenone Undecylenate on the market. It is also due to many often expecting benefits from the steroid that it is not intended to provide. If you're expecting enormous increases in mass due to this steroid's use, you're going to be disappointed. However, some associate the quality of a steroid only on the basis of its ability to promote mass, and inevitably they give Boldenone Undecylenate a bad name. Mass promotion is not the only way anabolic steroids are to be judged; unfortunately, this way of thinking has plagued many steroid message boards for quite sometime and greatly damaged anabolic steroid education. Boldenone Undecylenate can be an excellent addition to a well-planned cycle, but you must understand what it can provide and how it can benefit you in order to get the most out of it.
Profile
- Base : Boldenone
- Ester : Undecylenate
- Chemical name : [1,4-androstadiene-3-one,1 7b-ol] [1-dehydrotestosterone]
- Molecular Weight (base) : 286.4132
- Molecular Weight (ester) : 186.2936
- Formula (base) : C19H26O2
- Manufacturer : Various
- Effective Dose (Men) : 200-600mgs/week
- Effective Dose (Women) : 50-100mgs/week
- Active life : 15 days
- Detection Time : Up to 5 months
- Anabolic/ Androgenic ratio : 100:50
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